Scientific research and studies
There are, of course, a great many different types of tumors. Some tumors are often much more treatable than others. Scientists are constantly searching for innovative treatments. But this requires more knowledge about these tumors.
In the fall of 2024, our working group asked scientists to organize a workshop on scientific research into brain tumors and treatments. Below, you can read a summary of what they are currently working on. We can only try to support and encourage where possible, and together we hope for a breakthrough...
Brain tumor research: from cell culture to mouse model
Developing better treatments for brain tumors requires a thorough understanding of how these tumors develop, grow, and respond to therapy. Because research in patients is naturally limited, scientists use experimental models that mimic the tumor.
In the laboratory, we work with various types of models. In vitro models—such as cell lines and three-dimensional cultures (organoids)—enable us to study tumor cells directly. These models are particularly well-suited for testing targeted therapies that target the genetic or molecular characteristics of the tumor. They offer a controlled and efficient way to pre-evaluate promising substances.
Mouse models are crucial for researching the effect of a treatment in a living organism—for example, in combination with the immune system for immunotherapy. These models allow us to study the interaction between tumor and immune system, and to investigate how a treatment works throughout the body. They are therefore a vital link between fundamental research and clinical applications.
By using both simple and more complex in vitro models, as well as in vivo animal models, we are gradually building a better understanding of brain tumors and developing more effective, more personalized treatments."
Prof. Dr. Ir. Frederik De Smet
There may be numerous research centers in Europe and the rest of the world searching for solutions, and let's hope that promising news about new treatments will emerge in the coming years. If any readers are engaged in scientific research that might be interesting to share on this website, we'd love to hear from them. We're also certainly willing to participate in projects or fundraising activities to support this research wherever possible. It's through collaboration that progress is achieved.
